Most patients with glioblastoma, the same brain cancer Sen. John McCain has, begin their medical treatment with radiation and chemotherapy. Many times, however, the cancer returns.

What are patients’ options after all known treatments have failed? The answer could be in one of dozens of clinical trials throughout the country looking for new ways to fight cancer.

Immunotherapy, vaccines, medications and a combination of these treatments are being studied.

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A rendering of the columbarium memorial that is estimated to be completed by next summer or fall in the southeast part of Oakland Cemetery, officials said. (Courtesy of Historic Oakland Foundation)

Credit: Historic Oakland Foundation